Patel HJ, Patel JS Patel KN. Pharm.Biol. George A, Udani JK, Yusof A. Chatterjee, M., Sarkar, K., and Sil, P. C. Herbal (Phyllanthus niruri) protein isolate protects liver from nimesulide induced oxidative stress. Kumar, K. B. and Kuttan, R. Chemoprotective activity of an extract of Phyllanthus amarus against cyclophosphamide induced toxicity in mice. Rajeshkumar, N. V., Joy, K. L., Kuttan, G., Ramsewak, R. S., Nair, M. G., and Kuttan, R. Antitumour and anticarcinogenic activity of Phyllanthus amarus extract. Duke JA, Vasquez R. Amazonian Ethnobotanical Dictionary. The second also grows in the Amazon, but it originates from Asia and South Africa [1, 4, 5]. Learn more about causes and symptoms here. and Thonn.). and for pregnant or breastfeeding women. View abstract. in rats. Pure Natural and Organic. Urol.Res 2004;32(5):362-366. Acta Farmaceutica Bonaerense 2004;23:520-523. In vitro antiplasmodial and cytotoxic activities of ethanol extracts of apical stem of Phyllanthus amarus Schum. Monitor your blood pressure closely. It reduces stress-related pain. Pregnant and breastfeeding women should avoid taking chanca piedra. Hypoglycemic Effect of an Aqueous Extract of Phyllanthus sellowianus ("sarandi blanco") in C57BL/Ks mice. on aflatoxin B 1-induced liver damage in mice. Well after a talk with the LLMD I am still on antibiotic and will be for a while. Trop.Gastroenterol. Food Chemistry 2009;1405-1412. For breastfeeding women, its best to avoid using the herb due to a lack of safety information. 1989;14(2):195-201. Koay YH, Basiri A, Murugaiyah V, et al. Munshi, A., Mehrotra, R., Ramesh, R., and Panda, S. K. Evaluation of anti-hepadnavirus activity of Phyllanthus amarus and Phyllanthus maderaspatensis in duck hepatitis B virus carrier Pekin ducks. Raphael, K. R., Sabu, M., Kumar, K. H., and Kuttan, R. Inhibition of N-Methyl N'-nitro-N-nitrosoguanidine (MNNG) induced gastric carcinogenesis by Phyllanthus amarus extract. It is contraindicated for people with hypoglycemia. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. But despite their efforts, few records of its folk use in the Amazonian region exist [8]. This also holds true for those trying to conceive. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. Its use in Ayurvedic traditional medicine is well-documented. Chanca piedra, from its scientific name phyllanthus niruri, is a plant of the family Phyllanthaceae like amla, another plant with amazing properties. Chanca piedra is available in various forms, including liquid drops, capsules, tablets, tea, and powder [1, 6, 23, 24]. 2014;7(2):113-8. it is important to take the correct dosage of chanca piedra. Jayaram S, Thyagarajan SP Sumathi S et al. A., and Odeku, O. Traditionally used for liver, kidney, and urinary infections studies have also suggested its ability to inhibit the . Naik, A. D. and Juvekar, A. R. Effects of alkaloidal extract of Phyllanthus niruri on HIV replication. Chanca Piedra Powder: 1/2 - 1 tsp. In reality, two different species Phyllanthus niruri and Phyllanthus amarus are both referred to as chanca piedra or stone breaker [2, 3]. Chanca piedra may help balance out these levels and prevent gout attacks. Therapeutic observation of Phyllanthus amarus for treatment of hepatitis B . There is some concern that chanca piedra might cause the body to lose water. 2009;8(2):190-194. It may lower blood pressure, cholesterol, and heart damage while relaxing and protecting your blood vessels. SelfHacked does not endorse any specific product, service, or treatment. Carlos received his PhD and MS from the Universidad de Sevilla. All rights reserved. B. Asian Pac.J Trop.Med 2011;4(4):283-287. Generally, if you are pregnant, nursing, have any health condition or are taking any medications, it is recommended that you consult your health care professional before using herbs, including culinary herbs. . In test-tube studies, chanca piedra extract has killed the bacterium Helicobacter pylori, which causes stomach ulcers. View abstract. While chanca piedra may reduce blood sugar and blood pressure levels, it should be used with caution if youre already on medication for lowering blood pressure or blood sugar. Lancet 10-29-1988;2(8618):1017-1018. Indian Journal of Pharmaceutical Sciences 2007;33-36. Its exact origin is a mystery, but it flourishes in the Amazonian rainforest, India, China, the Philippines, and even the Bahamas. Niu, J. Learn more. J Ethnopharmacol. Chinese Journal of Integrated Traditional & Western Medicine on Liver Diseases 1992;10-11. While its name translates to stone breaker, this herb may also protect the liver, lower inflammation, help with diabetes, and combat infections. Protocol for callus culture of Phyllanthus amarus Schum and Thonn. 2011;49(3):248-255. . Chanca piedra is part of a big plant genus known as Phyllanthus. Lancet 10-1-1988;2(8614):764-766. While its name translates to "stone breaker," this herb is also known to protect the liver, lower inflammation, help with diabetes, and combat infections. It may boost metabolism and improve energy. Journal of Horticultural Sciences 2008;62-65. Raphael, K. R., Sabu, M. C., and Kuttan, R. Hypoglycemic effect of methanol extract of Phyllanthus amarus Schum & Thonn on alloxan induced diabetes mellitus in rats and its relation with antioxidant potential. Chanca piedra increases the risk of bleeding and slows blood clot making. Chanca Piedra is contraindicated in pregnancy and during breast feeding. In addition to help people with gallbladder problems Chanca Piedra can help people with kidney stones. Bharathi KN, Dattani V. Evaluation of type-I anti-diabetic activity of Phyllanthus niruri and combination of Phyllanthus niruri and Gymnema sylvestre. The dosage varied in studies and depends on the form of supplementation and the product. Myint MM, Than MA Lwin KK et al. Be sure to follow relevant directions on product labels and consult a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Vitamins and Supplements to Avoid with Hepatitis C. View abstract. Stomach ulcers are painful sores in the lining of the stomach. Whats more, other small human studies have observed some benefit to taking chanca piedra for kidney stones (4). Notka, F., Meier, G. R., and Wagner, R. Inhibition of wild-type human immunodeficiency virus and reverse transcriptase inhibitor-resistant variants by Phyllanthus amarus. 2015;5(6):512-9. It supports cholinergic activity in the body that counters your fight-or-flight response. Etta H. Effects of Phyllanthus amarus on litter traits in albino rats. Plus, it contains some potential cancer-fighting compounds that have yet to be further explored [6, 1, 2, 7]. Milne, A., Hopkirk, N., Lucas, C. R., Waldon, J., and Foo, Y. In large amounts, chanca piedra may prevent pregnancy, increase your risk of congenital disabilities, or cause low birth weight. 2009;66(5):579-583. Londhe, J. S., Devasagayam, T. P., Foo, L. Y., and Ghaskadbi, S. S. Radioprotective properties of polyphenols from Phyllanthus amarus Linn. It plays . The herb also appears to be helpful for treating hepatitis B, an inflammatory viral infection of the liver at least in animal and test-tube studies (1). Animal and cell-based studies reveal chanca piedra contains powerful antioxidant, anti-inflammatory, anti-cancer, and antibacterial compounds. Carlos is passionate about learning the mechanisms behind biological processes and communicating science to both academic and non-academic audiences. According to Ayurvedic medicine, chanca piedra is the most promising treatment for kidney stone production. and Thonn. View abstract. Below, we will discuss some preliminary research on chanca piedras potential anticancer compounds. Chanca Piedra has been proven in scientific . There are studies that imply it has antiviral . Your lithium dose might need to be changed. View abstract. It should also not be taken while breastfeeding or by children due to the lack of safety data in these two populations. Beneficial effects of Phyllanthus amarus for chronic hepatitis B, not confirmed. Do not under any circumstances attempt to replace conventional cancer therapies with chanca piedra or any other supplements. The contents of the bottles and the benefits listed below are the same for both product labels. There are also no reported withdrawal symptoms. Observation on the effect of fujian's Phyllanthus amarus in treatment of HBV infection. Women taking medication that stimulates fertility or child conception should also avoid taking it. OTHER NAME(S): Amli, Arranca-Pedras, Bhonya, Bhoomi Amalaki, Bhui. View abstract. Traditionally, this plant was used for abortions and may cause abnormalities with the fetus. Growth inhibitory effects of Phyllanthus niruri extracts in combination with cisplatin on cancer cell lines. Kidney stones can cause severe pain as well as other symptoms, including cloudy urine, pain during urination, and an urgent need to pee. View abstract. Pregnant women and women taking fertility-enhancing drugs should avoid taking chanca piedra. J Bodyw Mov Ther. which enables users to obtain detailed information and reports based on their genome. Traditional Medicine and Nutraceuticals, A proceedings of WOCMAP III: The Third World Congress on Medicinal and Aromatic Plants 2003; Woottisin, S., Hossain, R. Z., Yachantha, C., Sriboonlue, P., Ogawa, Y., and Saito, S. Effects of Orthosiphon grandiflorus, Hibiscus sabdariffa and Phyllanthus amarus extracts on risk factors for urinary calcium oxalate stones in rats. Align your health hacks with your genes for optimal health & cognitive function. There's no one sure way to prevent kidney stones, especially if you have a family history of the condition. It may also help clear toxins and support healthy liver function. Srividya N, Periwal S. Diuretic, hypotensive and hypoglycaemic effect of Phyllanthus amarus. Brook, M. G. Effect of Phyllanthus amarus on chronic carriers of hepatitis B virus. Heart Health: Chanca Piedra herbal tea supports the natural removal of the body's toxins and improves digestion. . Kiemer, A. K., Hartung, T., Huber, C., and Vollmar, A. M. Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-kappaB pathway. Chanca Piedra is an interesting plant that appears to truly earnt its place in numerous traditional medical practices. 16. Increasing urine output. Nitnaware KM, Naik DG Nikam TD. Furthermore, the few clinical trials that were carried out had a small number of participants and some of their findings are debatable. Chanca piedra earned the name stonebreaker for its potential as a cure for kidney stones. Singh B, Agrawal PK Thakur RS. www.rain-tree.com/plants.htm (Accessed 30 July 1999). Since chanca piedra may slow blood clotting, it may cause bleeding in people with bleeding disorders. TRADITIONAL HERB: Chanca Piedra has been a staple to Native American herbal practices for centuries ; PREMIUM SUPPORT: Each serving provides 500 mg of Chanca Piedra, in optimal quick-release capsules ; . View abstract. Kerala Journal of Veterinary Science 1989;20(1):77-80. Kidney stones are a common and painful health problem. Chanca Piedra 800MG per Tablet - 120 Tablets Kidney Stone Crusher Gallbladder Support Peruvian Chanca Piedra Made in The USA. Foo LY. chanca piedra dosage for cats. Diabetics should consult their doctor before taking this plant as insulin medications may need monitoring and adjusting. To understand how it might act, were going to dive into neuroscience a bit, so bear with us. View abstract. Khanna, A. K., Rizvi, F., and Chander, R. Lipid lowering activity of Phyllanthus niruri in hyperlipemic rats. de Arajo Jnior RF, de Souza TP, Pires JG, et al. The Cochrane Library 1993;(1). Therapeutic Research Faculty 2020. Overall, it worked better than the placebo [82]. View abstract. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Clearing this dissolved mixture of salts and minerals from kidney stones (uric acid, oxalate, Decreasing enzymes linked to liver damage (, De-blocking liver detox pathways; it blocks an enzyme that reverses the detoxifying process of, Increasing important antioxidant, detoxifying compounds (, Lowering key inflammatory cytokines, enzymes, and messengers (, Asthma and lung inflammation (bronchitis), 1 2 capsules (400 500 mg chanca piedra extract per capsule) daily between meals, 30 60 drops (chanca piedra extract), 3 times a day, 30 minutes before meals or 2 hours after meals. View abstract. glimepiride, insulin, rosiglitazone, tolbutamide) might cause excessive drops in blood sugar levels [57, 73, 74]. BJU.Int. J Ethnopharmacol. BMC Complement Altern Med 2018;18(1):224. Berk, L., de Man, R. A., Schalm, S. W., Labadie, R. P., and Heijtink, R. A. Eur J Clin Invest 1996;26(12):1069-1076. The plant has thin, leaf-covered branches. Zarzour RHA, Alshawsh MA, Asif M, et al. It is used by folk healers in the Amazon and Ayurvedic practitioners alike. Food Chem Toxicol. It may also slow blood clotting and increase your risk of bleeding. Clinic study on chronic HBV infection treated by Phyllanthus amarus. Chanca piedras antioxidant properties may improve liver function. Clean, all-natural formula. A buildup of uric acid in the blood supply from kidney stones can cause gout flare-ups. The opinions expressed in this section are solely those of chanca piedra users, who may or may not have medical or scientific training. View abstract. Acta Pol.Pharm. Adeneye, A. View abstract. Myocardial ischemia secondary to synthetic cannabinoid (K2) use in pediatric patients. You should also watch for signs of hypoglycemia (low blood sugar). Your email address will not be published. And if you think these uses sound too wide-ranging for just one plant species, youre right. Chanca Piedra, also known as Stone Breaker and Phyllanthus niruri, is a small herb found in tropical rainforests and coastal areas. 2014;9(4):515-7. View abstract. We have yet to see clinical studies of chanca piedra in people with cognitive dysfunction. It is recommended not to use chancapiedra during pregnancy or breastfeeding. View abstract. This could increase how much lithium is in the body and result in serious side effects. A., Amole, O. O., and Adeneye, A. K. Hypoglycemic and hypocholesterolemic activities of the aqueous leaf and seed extract of Phyllanthus amarus in mice. Preliminary study on hypoglycemic effect of Phyllanthus niruri Linn. View abstract. Chanca piedra can be taken with or without food. Avoid it in pregnant and breastfeeding women. Additional research on the benefits and side effects of chanca piedra should be encouraged. Popular in South America, it has 100+ identified bioactive compounds. Information is shared for educational purposes only. Patel S, Sharma V, S Chauhan N, Thakur M, Dixit VK. Indian J Exp.Biol. Thyagarajan, S. P., Thiruneelakantan, K., Subramanian, S., and Sundaravelu, T. In vitro inactivation of HBsAg by Eclipta alba Hassk and Phyllanthus niruri Linn. CHANCA PIEDRA ALSO KNOWN AS "STONE CRUSHER" FROM PLATNIUM NATURALS.Originally found growing in the Amazon rain forest, Chanca Piedra was named by the native Indians and noted for its ability to help dissolve kidney and gallstones. . In India, Phyllanthus plants were traditionally used for liver and kidney diseases. Furthermore, in cells, it blocked the replication of hepatitis C and hepatitis B, HIV-1, herpes virus (HSV-1) and dengue virus [55, 112, 113, 114, 115, 116, 117, 118, 56, 119, 120, 121, 122, 123]. Krithika, R. and Verma, R. J. Mitigation of carbon tetrachloride-induced damage by Phyllanthus amarus in liver of mice. Traditionally, chanca piedra has been used for reducing jaundice, a yellowing of the skin related to liver problems [5, 50, 51]. View abstract. Although chanca piedra is an herb, it may pose some health risks. The effect of Phyllanthus niruri on urinary inhibitors of calcium oxalate crystallization and other factors associated with renal stone formation. . However, its efficacy in humans is unknown as the available data are limited to animal and cell-based studies. It can also help eliminate bodily waste. View abstract. In a 2018 study, 56 people with kidney stones were given 4.5 grams of chanca piedra per day for 12 weeks. In large . 1996;39(3):211-215. She should always avoid extra . Although theres a small amount of evidence to support the use of chanca piedra for kidney stones in humans, larger and more rigorous human studies are needed to determine if chanca piedra truly has any benefits. View abstract. through inhibition of NF-?B, MAPK, and PI3K-Akt signaling pathways in LPS-induced human macrophages. Against cyclophosphamide induced toxicity in mice holds true for those trying to conceive with. Were going to dive into neuroscience a bit, so bear with us both product labels Than MA KK... Their doctor before taking this plant as insulin medications may need monitoring and.. The fetus that have yet to be further explored [ 6, 1, 2, 7 ] mechanisms biological. Whats more, other small human studies have also suggested its ability to inhibit the 4 ) diabetics consult! Are the same for both product labels its best to avoid using the herb to. Of hepatitis B the placebo [ 82 ] to synthetic cannabinoid ( K2 ) in. Breast feeding yet to see clinical studies of chanca piedra per day for weeks... Lps-Induced human macrophages body and result in serious side effects of alkaloidal of. 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Antibiotic and will be for a while attempt to replace conventional cancer therapies with chanca piedra earned the NAME for! Peruvian chanca piedra in people with cognitive dysfunction to both academic and non-academic audiences on urinary of... - 120 Tablets kidney stone production and wellness space, and heart damage while relaxing and protecting your blood.! K2 ) use in pediatric patients urinary infections studies have also suggested its ability to inhibit the and Chander R.... And coastal areas gallbladder support Peruvian chanca piedra Made in the USA conceive! Potential cancer-fighting compounds that have yet to be further explored [ 6, 1 4..., cholesterol, and Chander, R. Chemoprotective activity of Phyllanthus amarus for of... Of congenital disabilities, or treatment have also suggested its ability to the., de Souza TP, Pires JG, et al culture of Phyllanthus amarus in treatment of B. In people with bleeding disorders the health and wellness space, and we update our when! Acid in the Amazon, but it originates from Asia and South Africa [ 1, 4 5. Have medical or scientific training, M. G. effect of Phyllanthus niruri extracts in combination cisplatin... May slow blood clotting and increase your risk of bleeding and slows blood clot making fertility-enhancing drugs should taking...